BDBM50011446 2-(4-Hydroxy-phenyl)-chromen-4-one::2-(4-hydroxyphenyl)-4H-chromen-4-one::4'-hydroxyflavone::CHEMBL327209::NSC-22357

SMILES Oc1ccc(cc1)-c1cc(=O)c2ccccc2o1

InChI Key InChIKey=SHGLJXBLXNNCTE-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50011446   

TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Birla Institute of Technology

LigandPNGBDBM50011446(2-(4-Hydroxy-phenyl)-chromen-4-one | 2-(4-hydroxyp...)
Affinity DataKi:  1.05E+3nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Birla Institute of Technology

LigandPNGBDBM50011446(2-(4-Hydroxy-phenyl)-chromen-4-one | 2-(4-hydroxyp...)
Affinity DataKi:  5.06E+3nMAssay Description:The activities of recombinant hMAO-A and hMAO-B were determined using p-tyramine as common substrate and calculated as 0.18 +/- 0.01 nmol/mg/min (n =...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011446(2-(4-Hydroxy-phenyl)-chromen-4-one | 2-(4-hydroxyp...)
Affinity DataIC50:  4.19E+5nMAssay Description:Inhibition of p56 lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50011446(2-(4-Hydroxy-phenyl)-chromen-4-one | 2-(4-hydroxyp...)
Affinity DataIC50:  5.04E+5nMAssay Description:Ability to inhibit protein-tyrosine kinase activity of p56lck (isolated from bovine thymus) in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed